Biomedical sciences publications
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Formulation and in Vitro Characterization of Spray-Dried Antisense Oligonucleotide to NF-Kappa B Encapsulated Albumin Microspheres
The aim of this study was to formulate and characterize microspheres containing antisense oligonucleotide to NF-κB using bovine serum albumin as the polymer matrix.
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Caffeine Elicits c-Fos Expression in Horizontal Diagonal Band Cholinergic Neurons
We determined the effects of caffeine on cholinergic neuron activation in the rat basal forebrain.
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SR16157 Is a Potent Dual-Acting Inhibitor of Estrogen Biosynthesis and Estrogen Receptor
Using in vitro and xenograft MCF-7 breast cancer models, we demonstrated that SR16157 inhibited STS activity, cell growth, and estrogenic functions and that SR16137 reduced expression of estrogen-regulated genes with greater potency…
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Perception of Mercury Contamination By Brazilian Adolescents in a Gold Mining Community: An Ethnographic Approach
This study used ethnographic methods to examine the perception of mercury contamination by adolescents in the mining community of Poconé, Mato Grosso, Brazil.
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Contribution of Regional White Matter Integrity to Visuospatial Construction Accuracy, Organizational Strategy, and Memory for a Complex Figure in Abstinent Alcoholics
Visuospatial construction ability as used in drawing complex figures is commonly impaired in chronic alcoholics, but memory for such information can be enhanced by use of a holistic drawing strategy…
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Brain Injury and Recovery Following Binge Ethanol: Evidence from in Vivo Magnetic Resonance Spectroscopy
The current in vivo magnetic resonance (MR) imaging and spectroscopy study was conducted to test the hypothesis that binge EtOH exposure would injure but not cause the death of neurons…
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Decreased Alpha-Synuclein Expression in the Aging Mouse Substantia Nigra
Here we compared α-synuclein expression in the substantia nigra and other brain regions of young (2-month-old), middle-aged (10-month-old), and old (20-month-old) mice.
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Mechanisms of Postural Control in Alcoholic Men and Women: Biomechanical Analysis of Musculoskeletal Coordination During Quiet Standing
Whether alcoholic men and women who have remained abstinent from alcohol for weeks to months differ from each other in the degree of residual postural instability and biomechanical control mechanisms…
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Selective Deficiency of HIF-1 Alpha in Myeloid Cells Influences Secondary Intention Wound Healing in Mouse Skin
In this study we examined the role of myeloid cell HIF-1α on wound healing in vivo using a cell-specific knockout (KO) mouse model.
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Influence of Formulation Factors on Tablet Formulations with Liquid Permeation Enhancer Using Factorial Design
Factorial design was used to evaluate the effect of three formulation factors: drug percentage, polymer type, and tablet binder percentage on tablet characteristics.
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Formulation and in Vitro Characterization of Spray-Dried Antisense Oligonucleotide to Nf-B Encapsulated Albumin Microspheres
The aim of this study was to formulate and characterize microspheres containing antisense oligonucleotide to NF-κB using bovine serum albumin as the polymer matrix.
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Alcohol Consumption and Lung Cancer Risk in the Environment and Genetics in Lung Cancer Etiology (Eagle) Study
The authors investigated the relation between alcohol consumption and lung cancer risk in the Environment and Genetics in Lung Cancer Etiology (EAGLE) Study, a population-based case-control study.