Publications
-
Efficient Variable Elimination for Semi-Structured Simple Temporal Networks with Continuous Domains
We show that for an Simple Temporal Network, messages can be represented compactly as sub-STNs. We then present an efficient message-passing scheme for computing the minimal constraints of an STN.
-
Nonprofits and the Valley of Death in Drug Discovery
The research and development (R&D) process that ultimately leads to effective drugs is exceedingly difficult, and often the public does not understand the drug discovery pipeline.
-
Resequencing of Nicotinic Acetylcholine Receptor Genes and Association of Common and Rare Variants with the Fagerstrom Test for Nicotine Dependence
We investigated the contribution of common SNPs and rare single-nucleotide variants in nAChR genes to Fagerström test for nicotine dependence scores in treatment-seeking smokers.
-
Alpha-Synuclein Suppression By Targeted Small Interfering RNA in the Primate Substantia Nigra
The protein α-synuclein is involved in the pathogenesis of Parkinson's disease and other neurodegenerative disorders.
-
The CALO meeting assistant system
This paper presents the CALO-MA architecture and its speech recognition and understanding components.
-
Creation of a Genome-Wide Metabolic Pathway Database for Populus Trichocarpa Using a New Approach for Reconstruction and Curation of Metabolic Pathways for Plants
We developed a general approach for reconstructing metabolic pathway complements of plant genomes.
-
Language Analytics for Assessing Brain Health: Cognitive Impairment, Depression and Pre-Symptomatic Alzheimer’s Disease
We present data demonstrating how brain health may be assessed by applying data-mining and text analytics to patient language.
-
α-Synuclein Suppression By Targeted Small Interfering RNA in the Primate Substantia Nigra
Here, feasibility and safety of α-synuclein suppression were evaluated by treating monkeys with small interfering RNA (siRNA) directed against α-synuclein.
-
Designing, Deploying, and Operating Instrumentation in the Polar Regions
The 6th annual Polar Technology Conference was held to discuss technical challenges and innovative solutions for polar research.
-
Further Characterization of Sleep-Active Neuronal Nitric Oxide Synthase Neurons in the Mouse Brain
The present study was undertaken to evaluate the specificity of this state-dependent activation of cortical nNOS cells from the previous study.
-
On the Life-Cycle of BDI Agent Goals
Systems based on the well-known Belief-Desire-Intention (BDI) framework most often ascribe a set of goals to the agent, which is equipped with various techniques to deliberate over and manage this…
-
Material Property Requirements for Analysis and Design of Uhtc Components in Hypersonic Applications
We explain the nature of the analyses, highlight the essential material properties that are required and why they are important, and describe the impact of property accuracy and uncertainty on…