SRI International
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Coordinated Ionospheric Observations Indicating Coupling between Preonset Flow Bursts and Waves That Lead to Substorm Onset
A critical, long-standing problem in substorm research is identification of the sequence of events leading to substorm expansion phase onset.
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GABAB Agonism Promotes Sleep and Reduces Cataplexy in Murine Narcolepsy
We evaluated the effects of chronic administration of GHB and the GABA B agonist R -baclofen ( R -BAC) on arousal state and cataplexy in two models of narcolepsy: orexin/ataxin-3 (Atax) and orexin/tTA; TetO diphtheria toxin mice (DTA).
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Conditional Ablation of Orexin/Hypocretin Neurons: A New Mouse Model for the Study of Narcolepsy and Orexin System Function
The sleep disorder narcolepsy results from loss of hypothalamic orexin/hypocretin neurons. Although narcolepsy onset is usually postpubertal, current mouse models involve loss of either orexin peptides or orexin neurons from birth. To create a model of orexin/hypocretin deficiency with closer fidelity to human narcolepsy, diphtheria toxin A (DTA) was expressed in orexin neurons under control…
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A Novel Scheme for Speaker Recognition Using a Phonetically-Aware Deep Neural Network
We propose a novel framework for speaker recognition in which extraction of sufficient statistics for the state-of-the-art i-vector model is driven by a deep neural network (DNN) trained for automatic speech recognition (ASR).
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ASR Error Detection Using Recurrent Neural Network Language Model and Complementary ASR
Our goal is to locate errors in an utterance so that the dialogue manager can pose appropriate clarification questions to the users.
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An Autoencoder with Bilingual Sparse Features for Improved Statistical Machine Translation
We propose a natural autoencoder that maps all the discrete and overlapping sparse features for each SCFG rule into a continuous vector, so that the information encoded in sparse feature vectors becomes a dense vector that may enjoy more samples during training and avoid overfitting.
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Computationally-Efficient Endpointing Features for Natural Spoken Interaction with Personal-Assistant Systems
We elicit personal-assistant speech using a recognizer with a dramatically increased endpoint threshold, and find frequent non-final pauses. Based on the new data, we develop low-cost acoustic features to discriminate non-final from final pauses.
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Dissociation of Preparatory Attention and Response Monitoring Maturation During Adolescence
The objective was to assess development of EEG markers of these strategies and their role in both preparatory attention (contingent negative variation, CNV) and response monitoring (Error Related Negativity, ERN, and Correct Related Negativity, CRN).
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SENSOR: embedded fiber optic sensing for accurate state estimation in advanced battery management systems
Under the ARPA-E AMPED program for advanced battery management systems (BMS), PARC and LG Chem Power are developing SENSOR (Smart Embedded Network of Sensors with an Optical Readout), an optically based smart monitoring system prototype targeting batteries for hybrid and electric vehicles (EVs).
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Embedded Fiber Optic Chemical Sensing for Internal Cell Side-Reaction Monitoring in Advanced Battery Management Systems
This paper focuses on in situ FO chemical sensing methods tailored for accurate cell side-reaction monitoring.
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Identification and optimization of PDE10A inhibitors using fragment-based screening by nanocalorimetry and X-ray crystallography
Here we use enthalpy arrays, which are arrays of nanocalorimeters, to perform an enzyme activity-based fragment screen for competitive inhibitors of phosphodiesterase 10A (PDE10A).
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Community Colleges Provide Invaluable Stepping Stone for Autistic Youth
Community colleges may provide a smoother transition to the academic and social challenges that can arise in a university setting. These institutions may be particularly appealing for students with autism spectrum disorders (ASDs) to pursue postsecondary education while still remaining at home, where they have the continuity of family support and a consistent environment. To…