SRI International
-
Tumor-specific intracellular delivery: peptide-guided transport of a catalytic toxin
Here we optimize our lead peptide by a series of chemical modifications including truncations, N-terminal capping, and changes in valency.
-
Ancient origin and conserved gene function in terpene pheromone and defense evolution of stink bugs and hemipteran insects
The origin of enzymes involved in terpene biosynthesis and their evolution in insect genomes is still poorly understood. We addressed this question by investigating the evolution of isoprenyl diphosphate synthase (IDS)-like genes with terpene synthase function in the family of stink bugs.
-
SRI researchers are working to build the knowledge management technology of the future
Funded by a $10.8 million Defense Advanced Research Projects Agency contract, the initiative aims to transform how organizations store and manage data.
-
Vidyasagar Sadhu
Advanced Computer Scientist, Artificial Intelligence Center (AIC)
-
Women participants needed for NIH funded research study on memory and sleep
We are looking for healthy women to participate in an NIH funded research study exploring the impact of sex hormones on memory and sleep.
-
Transforming High Schools to Serve Students Who Are Off Track to Graduate: Lessons Learned from the Engage New England Initiative
This brief presents lessons learned about school transformation from the Barr Foundation’s Engage New England initiative, an effort to catalyze high school innovation by developing exemplary schools that support the success of students who are off track to graduate.
-
CEE 101: An Introduction to Coordinated Eligibility
We describe what CEE is, how to do it, what the benefits are, key decisions that must be made, and facilitators and barriers to implementation.
-
Social Epidemiology of Early Adolescent Cyberbullying in the United States
Our objective was to determine the prevalence and sociodemographic correlates of cyberbullying victimization and perpetration among a diverse population-based sample of adolescents.
-
Wearable and mobile technology to characterize daily patterns of sleep, stress, presleep worry, and mood in adolescent insomnia
There is a bidirectional relationship between daily stress and sleep, with daily stress negatively impacting sleep, which in turn leads to more stress in adolescents with and without insomnia symptoms.
-
The development of sleep/wake disruption and cataplexy as hypocretin/orexin neurons degenerate in male vs. female Orexin/tTA; TetO-DTA Mice
We compared the development of narcoleptic symptomatology in male vs. female orexin-tTA; TetO-DTA mice, a model in which Hcrt neuron degeneration can be initiated by removal of doxycycline (DOX) from the diet.
-
Screen Time and Obsessive-Compulsive Disorder Among Children 9–10 Years Old: A Prospective Cohort Study
The aim of this study is to determine the prospective associations between baseline screen time and obsessive-compulsive disorder (OCD) at 2-year follow-up in a national (United States) cohort of 9- to 10-year-old children.
-
The role of ovarian hormones in the pathophysiology of perimenopausal sleep disturbances: A systematic review
We reviewed the literature about the influence of ovarian hormones on sleep in perimenopausal women, summarize the potential underlying pathophysiology of menopausal sleep disturbances and evaluate the implications of these findings for the therapeutic approach to sleep disturbances in the context of menopause.