Author: SRI International
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Epigenetic Alteration of the Wnt Inhibitory Factor-1 Promoter Occurs Early in the Carcinogenesis of Barrett’s Esophagus
We hypothesized that downregulation of the Wnt inhibitory factor-1 (WIF-1) might be involved in the neoplastic progression of Barrett’s esophagus (BE).
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How Post-Secondary Journalism Educators Teach Advanced Car Data Analysis Skills In The Digital Age
Survey responses from 232 journalism educators in 33 nations were analyzed for descriptions of how they have taught a subset of the most pedagogically challenging computer-assisted reporting (CAR) skills-advanced data analysis.
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Identification of Novel Cyp2A6*1B Variants: the Cyp2A6*1B Allele Is Associated with Faster in Vivo Nicotine Metabolism
We report evidence that CYP2A6*1B genotype is associated with faster nicotine clearance in vivo, which will be important to future CYP2A6 genotype association studies.
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Systems Learning for Complex Pattern Problems
What are the principles behind long-term learning and development? We describe our efforts in this direction and discuss the many challenges.
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Usable Artificial Intelligence
The AI and HCI communities have often been characterized as having opposing views of how humans and computers should interact” observes Winograd in “Shifting Viewpoints”. Reconciling these views requires a thoughtful balancing of assistance and control, of mental and system representations, and of abstract process and contextualized workflow.
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Wiggling Into Traditional High School Curriculum
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Back-Illuminated Image Sensors Come to the Forefront
Recently, a breakthrough in novel materials and fabrication methods was achieved that will make higher-performance back-thinned imagers readily available for mass production. Using ultrathin silicon-on-insulator wafer technology, the method will reduce the manufacturing complexity and effectively solve the cost-quality challenge.
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Collaborative Effects of Mobile Sensor Network Localization Through Distributed Multimodal Navigation Sensor Fusion
This paper addresses the problem of localizing both absolute and relative 3-D positions of mobile sensor network nodes by fusing inertial measurements and radio frequency (RF) ranging measurements. Four online estimation algorithms are described.
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Comparative Study of SnO2- and In2O3- Based Ozone Sensors
In this paper we present the results of comparative study of ozone sensors that are designed using undoped SnO2 and In2O3 films.
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A Framework for Efficient and Composable Oblivious Transfer
We propose a simple and general framework for constructing oblivious transfer (OT) protocols that are efficient, universally composable, and generally realizable under any one of a variety of standard number-theoretic assumptions.
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Effect of Resveratrol on 17 Beta-Estradiol Sulfation By Human Hepatic and Jejunal S9 and Recombinant Sulfotransferase 1E1
Abstract The purpose of this study was to investigate the sulfation of resveratrol (3,5,4′-trihydroxystilbene) and its potential to exhibit drug-drug interactions via sulfation. The possible interaction of resveratrol with 17β-estradiol (E2), a major estrogen hormone and prototypic substrate for sulfate conjugation, was studied. Resveratrol and E2 are both known to undergo sulfate conjugation catalyzed by…
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Formulation and Evaluation of Albumin Microspheres and Its Enteric Coating Using a Spray-Dryer
This study optimized and evaluated the conditions for surface coating of microspheres using a spray-dryer. Four formulations of Bromophenol blue (BPB)-loaded albumin microspheres were prepared using a spray-dryer, cross-linked at different concentrations and time periods.