Biomedical sciences publications

Tumor glycomics research in recent years has uncovered a large panel of tumor-associated carbohydrate antigens and evidence of immune recognition of tumor-derived aberrant carbohydrates.

Here, we identify gaps in which computational approaches have been used for some neglected diseases and not others. We also make recommendations for the broad-spectrum integration of these techniques into…

This review focuses on the method developments in obtaining biologically active NC1 domains and for specific evaluations in different scenarios.

On the occasion of the second anniversary of the Fukushima disaster, it was reported inScience magazine that evacuees were still waiting to go home, but fortunately that radionuclide exposure, at…

We investigated memory performance and cardiovascular activity in 13 primary insomniacs (PI) compared to 13 good sleepers (GS).

Here, we investigated the role of MNF in GPR55 signaling in human HepG2 and PANC-1 cancer cell lines in culture by focusing first on internalization of the fluorescent ligand Tocrifluor…

Influenza is an infectious disease typically transmitted through the air. It is responsible for seasonal epidemics affecting millions of people, and sporadic global pandemics. Influenza infection is a membrane fusion‐dependant process, occurring…

In this report we describe and characterize two novel long-lived transgenic mouse models of Gba deficiency, along with a subchronic conduritol-ß-epoxide (CBE) exposure paradigm.

The new TDG vapor pressure data are in sharp contrast to widely accepted values from previous literature.

This paper reviews the anatomy of the primary organs (kidney, liver, and spleen) responsible for nanoparticle bioelimination and the components of the innate immune system (complement system and scavenger receptors)…

The relative utility of single biomarkers compared to biomarker panels is discussed, along with paradigms for biomarker development, the latter in the context of three large-scale biomarker consortia, the Critical…

The β2-adrenergic receptor (β2-AR) agonist [3H]-(R,R′)-methoxyfenoterol was employed as the marker ligand in displacement studies measuring the binding affinities (Ki values) of the stereoisomers of a series of 4′-methoxyfenoterol analogs in…