Biomedical sciences publications

Here, we investigated the role of MNF in GPR55 signaling in human HepG2 and PANC-1 cancer cell lines in culture by focusing first on internalization of the fluorescent ligand Tocrifluor…

Influenza is an infectious disease typically transmitted through the air. It is responsible for seasonal epidemics affecting millions of people, and sporadic global pandemics. Influenza infection is a membrane fusion‐dependant process, occurring…

In this report we describe and characterize two novel long-lived transgenic mouse models of Gba deficiency, along with a subchronic conduritol-ß-epoxide (CBE) exposure paradigm.

We report here the vitro characterization of this radioligand in receptor binding and in vitro autoradiographic studies targeting the α3β4* nAChR.

The purpose of this research work is to evaluate toxicity of diethylenetriamine pentaacetic acid zinc trisodium salt (Zn-DTPA) tablets.

We investigated whether QoL varies between women with and without severe primary dysmenorrhea, and whether QoL is impaired only during menstruation or also during pain-free phases of the menstrual cycle.

An HPLC method for the assay of the heat shock protein 90 inhibitor, PU-H71 (NSC 750424), has been developed and validated.

Tumor glycomics research in recent years has uncovered a large panel of tumor-associated carbohydrate antigens and evidence of immune recognition of tumor-derived aberrant carbohydrates.

Recent scientific advances have provided substantial information on the brain circuits and pathways relevant to various aspects of dependence. 

A new algorithm, developed with data from smoking cessation clinical trials and published practice guidelines, is designed to predict the likelihood of abstinence.

Here we describe the use of a neurotoxin, 1-methyl-4-phenyl-1,2,3,6-tetrahydropyridine (MPTP), which produces a nigrostriatal lesion to elucidate the distinct contributions of LOX isozymes to neurodegeneration related to PD.

Here, alcohol-preferring (P) and alcohol-nonpreferring (NP) rats systematically bred from heterogeneous stock Wistar rats for differential alcohol drinking behavior were compared with Wistar rats to determine whether genetic divergence and…