Biomedical sciences publications
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Combining Structure and Appearance Cues for Real-Time Pedestrian Detection
We present a real-time pedestrian detection system which uses cues derived from structure and appearance classification.
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Longitudinal Study of Callosal Microstructure in the Normal Adult Aging Brain Using Quantitative DTI Fiber Tracking
We present a review of neuroimaging studies of normal adult aging conducted with diffusion tensor imaging (DTI) and data from one of the first longitudinal studies using DTI to study…
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The Right Formulation – and How to Get There
This article by Gita Shankar, PhD, Director of Formulations R&D, Pharmaceutical Sciences at SRI, describes the strategy that the company uses to develop an appropriate formulation.
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A Bottom-Up Biofeedback Remediation Improves Emotion Recognition in Schizophrenia: Evidence from a Visual Scan Path Pilot Study
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Monocyte Dysfunction in Sydenham’s Chorea Patients
We evaluated the activation state of monocytes, cells that are precursors of macrophages, to characterize the inflammation profile of patients.
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Mouse Urinary Biomarkers Provide Signatures of Maturation, Diet, Stress Level, and Diurnal Rhythm
We compared the volatile compositions of mouse urine using solid-phase microextraction and gas chromatography–mass spectrometry (SPME-GC/MS).
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MR Diffusion Tensor Imaging: a Window Into White Matter Integrity of the Working Brain
Here we present an overview of the principles of diffusion tensor imaging (DTI) and its contribution to progress in our current understanding of normal and pathological brain function.
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Vaccination of Rabbits with an Alkylated Toxoid Rapidly Elicits Potent Neutralizing Antibodies Against Botulinum Neurotoxin Serotype B
New Zealand White (NZW) rabbits were immunized with several different nontoxic botulinum neurotoxin serotype B (BoNT/B) preparations in an effort to optimize the production of a rapid and highly potent,…
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Advanced Vehicle Tracking in Persistent Aerial Surveillance Video
This paper presents a relational graph based approach to track thousands of vehicles from persistent wide area airborne surveillance (WAAS) videos.
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Development of a New Generation of 4-Aminoquinoline Antimalarial Compounds Using Predictive Pharmacokinetic and Toxicology Models
ADMET prediction studies were employed to evaluate a library of new molecules based on the 4-aminoquinolone-related structure of CQ.
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Historical Insights Into Sleep Research
The article in the present issue by Basner helps to ensure the “virtuous actions” and careful insightful science of Ernst Otto Heinrich Kohlschütter will not be forgotten.
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The Puf-Family RNA-Binding Protein Pfpuf2 Regulates Sexual Development and Sex Differentiation in the Malaria Parasite Plasmodium Falciparum
In this study we determined the function of PfPuf2, a member of the Puf family of translational repressors, in gametocytogenesis of Plasmodium falciparum.