Publications
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A New Activated Carbon for CO2 Capture from Coal-Fired Boiler Flue Gas
With the current environmental interest in controlling greenhouse gases, there is a new focus on materials that can discriminate between gas molecules by capturing those gases that must be curtailed…
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Development of Functional Assays for p97/VCP Inhibition
We used p97 siRNA and a recently identified small molecule p97 inhibitor, N2,N4-dibenzylquinazoline- 2,4-diamine (DBeQ) as tools to develop functional assays suitable for further evaluating the activity of potential p97…
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Expanding Access to STEM-Focused Education: What Are the Effects?
Calls for broadening the population of students motivated and prepared to pursue STEM studies, with an aim ultimately to impact the country’s competitiveness, have been frequent and widespread...
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In Vivo Glutamate Measured with Magnetic Resonance Spectroscopy: Behavioral Correlates in Aging
To investigate the contribution of regional glutamate levels to behavior in the aging brain, we used an in vivo magnetic resonance spectroscopy protocol optimized for glutamate detection in 3 brain regions targeted by…
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SR16388 Impairs Protein Homeostasis and Induces Autophagy in Diverse Human Cancer Cell Lines
SR16388 is a novel amino steroid that targets estrogen-binding proteins including genomic estrogen receptors.
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Declaratively Processing Provenance Metadata
We propose a simple declarative language for processing provenance metadata and evaluate it by translating filters implemented in SPADE [9], an open-source provenance collection platform.
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Preparation and Spectroscopic Characterization of Chemical Derivatives of Lawsone: Novel Reagents to Detect Fingerprints
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Flexible Visuo-Haptic Display
We have developed a flexible electro-active polymer (EAP) actuator and a thin flexible visual display with 3×3 array configuration via polymer technology.
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Genetic Analysis of a Population Heavy Drinking Phenotype Identifies Risk Variants in Whites
This proof-of-concept analysis examined whether population data of lifetime heaviest alcohol consumption may be used to identify genetic loci that modulate risk.
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Midbrain-Driven Emotion and Reward Processing in Alcoholism
Enhanced midbrain activation to alcohol-related words suggests neuroadaptation of dopaminergic midbrain systems. We speculate that such tuning is normally associated with behavioral conditioning to optimize responses but here contributed to…
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A Systematic Screen of FDA-Approved Drugs for Inhibitors of Biological Threat Agents
The feasibility of repurposing existing drugs to face novel threats is demonstrated and this represents the first effort to apply this approach to high containment bacteria and viruses.
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The Ability of Plasma Cotinine to Predict Nicotine and Carcinogen Exposure Is Altered by Differences in CYP2A6: The Influence of Genetics, Race, and Sex
Cotinine, a nicotine metabolite, is a biomarker of tobacco, nicotine, and carcinogen exposure. However, a given cotinine level may not represent the same tobacco exposure; for example, African-Americans have higher…