Publications
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Development of Functional Assays for p97/VCP Inhibition
We used p97 siRNA and a recently identified small molecule p97 inhibitor, N2,N4-dibenzylquinazoline- 2,4-diamine (DBeQ) as tools to develop functional assays suitable for further evaluating the activity of potential p97…
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Expanding Access to STEM-Focused Education: What Are the Effects?
Calls for broadening the population of students motivated and prepared to pursue STEM studies, with an aim ultimately to impact the country’s competitiveness, have been frequent and widespread...
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WhoAmI: Profiling attendees before meetings
In this paper, we present the Meshin system, an intelligent personal assistant that organizes messages, notifications and appointments for mobile phone users.
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Data handling in the smart grid: do we know enough?
We propose here a research agenda to appropriately balance the advantages of fine-grained energy usage data with the associated privacy risks.
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Flexible, large-area sensor circuits fabricated by additive printing
Organic materials have been demonstrated as good candidates for large-area flexible sensors, because they allow wide tolerance of sensor geometry and thickness, which would ease fabrication problems such as strain…
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A “Conditional” Sense of Fairness in Assessment
This article builds on recent research in universal design for learning (UDL), assessment design, and psychometrics to lay out the rationale for inference that is conditional on matching examinees with…
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Mars Organic Molecule Analyzer (MOMA) Mass Spectrometer for Exomars 2018 and Beyond
The Mars Organic Molecule Analyzer (MOMA) investigation forms a core part of the sample analysis capability of ExoMars. Its top objective is to address the main “life signs” goal of…
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Biomarkers—an Essential Tie That Binds the Future of Drugs and Diagnostics
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Proteolytic Enzymes as Biomarkers of Focal Segmental Glomerulosclerosis
Here, the library was utilized to map the global proteolytic specificities of plasma samples obtained from patients with the nephrotic syndrome, known as focal segmental glomerulosclerosis (FSGS).
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The Nicotine-Mediated Decline in L-Dopa-Induced Dyskinesias Is Associated with a Decrease in Striatal Dopamine Release
This study investigates whether nicotine may exert its beneficial effects by modulating pre-synaptic dopaminergic function.
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Anti-Oligomannose Antibodies as Potential Serum Biomarkers of Aggressive Prostate Cancer
This study bridges a carbohydrate microarray discovery and a large-scale serological validation of anti-oligomannose antibodies as novel serum biomarkers of aggressive prostate cancer.
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Computing Minimal Nutrient Sets from Metabolic Networks Via Linear Constraint Solving
We present a method for computationally determining alternative growth media for an organism based on its metabolic network and transporter complement.