Publications
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The First Universal Opioid Ligand, (2S)-2-[(5R,6R,7R,14S)-N- Cyclopropylmethyl-4,5-Epoxy-6,14-Ethano-3-Hydroxy-6-Methoxymorphinan-7-Yl]-3, 3-Dimethylpentan-2-Ol (Bu08028): Characterization of the in Vitro Profile and in Vivo Behavioral Effects in Mouse Models of Acute Pain and Cocaine-Induced Reward
We hypothesized that ligands with buprenorphine's physical properties, but possessing increased NOP receptor affinity and efficacy, would improve the profile as a drug abuse medication and reduce addiction liability.
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Association of the Calcyon Neuron-Specific Vesicular Protein Gene (Caly) with Adolescent Smoking Initiation in China and California
These results suggest that the CALY gene may influence smoking initiation in adolescents, although the potential roles of underlying psychological characteristics remain to be explored.
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Spin-Orbit Coupling, Spin Relaxation, and Spin Diffusion in Organic Solids
We develop a systematic approach of quantifying spin-orbit coupling (SOC) and a rigorous theory of carrier spin relaxation caused by the SOC in disordered organic solids.
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A Collective Intelligence Based Business-Matching and Recommending System for Next Generation E-Marketplaces
The present work proposes and describes a novel approach to business-matching and recommending systems, for the next-generation e-marketplaces, with a focus on the needs and realities of small business.
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Pontocerebellar Contribution to Postural Instability and Psychomotor Slowing in HIV Infection Without Dementia
We examined whether infratentorial brain tissue volume would be deficient in nondemented HIV-infected individuals and whether selective tissue deficits would be related to postural stability and psychomotor speed performance.
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Association of the Nicotine Metabolite Ratio and CHRNA5/CHRNA3 Polymorphisms with Smoking Rate Among Treatment-Seeking Smokers
Genome-wide association studies have linked single-nucleotide polymorphisms (SNPs) in the CHRNA5/A3/B4 gene cluster with heaviness of smoking.
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Thermal and Electrical Transport Properties of Spark Plasma-Sintered HfB2 and ZrB2 Ceramics
The thermal conductivity was found to decrease with increasing temperature for all materials. Results are discussed in terms of sample morphology and compared with data previously reported in the scientific…
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Direct inhibition of hypocretin/orexin neurons in the lateral hypothalamus by nociceptin/orphanin FQ blocks stress-induced analgesia in rats
We tested the hypothesis that N/OFQ modulates the SIA directly via the inhibition of the Hcrt neurons in the lateral hypothalamus.
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Sleep and the Brain
This issue’s special section on “Sleep through the Ages” contains papers addressing the neurological and neuropsychological implications of sleep in adolescents, older adults and insomnia sufferers, highlighting relations of sleep…
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Changes in Sleep as a Function of Adolescent Development
While changes in sleep across adolescence are a normal part of development, many adolescents are getting insufficient sleep and are consequently, less likely to perform well at school, more likely…
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Competition Between Intradomain and Interdomain Interactions: a Buried Salt Bridge Is Essential for Villin Headpiece Folding and Actin Binding
We used mutational analysis, monitored by CD and NMR, and functional assays to determine the role of this buried salt bridge.
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A Melanoma Molecular Disease Model
This paper describes such a Melanoma Molecular Disease Model reflecting the latest scientific, clinical, and technological advances.