Publications
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Computational Databases, Pathway and Cheminformatics Tools for Tuberculosis Drug Discovery
Cheminformatic techniques have been leveraged and are examined in this review. We suggest that these computational approaches should be optimally integrated within a workflow with experimental approaches to accelerate TB…
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Tracking and Sketching Distributed Data Provenance
We describe a system for capturing data provenance in distributed applications, and the use of provenance sketches to optimize subsequent data provenance queries.
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Captopril Increases the Intensity of Monocyte Infection By Trypanosoma Cruzi and Induces Human T Helper Type 17 Cells
Here we showed that captopril increases the intensity of T. cruzi infection of human monocytes in vitro. The increased parasitism was accompanied by up-regulated expression of ACE in human monocytes.
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In Vivo MRSI of Hyperpolarized [1-13C]Pyruvate Metabolism in Rat Hepatocellular Carcinoma
We implemented a three-dimensional MRSI sequence to investigate this potential hallmark of cellular metabolism in rat livers bearing HCC (n = 7 buffalo rats).
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An Application Framework for Loosely Coupled Networked Cyber-Physical Systems
We describe a new paradigm for programming an NCPS that enables users to specify their needs and nodes to contribute capabilities and resources.
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Implementing SRI’s Pashto speech-to-speech translation system on a smartphone
We describe our recent effort implementing SRI's UMPC-based Pashto speech-to-speech (S2S) translation system on a smart phone running the Android operating system.
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PANTHER Version 7: Improved Phylogenetic Trees, Orthologs and Collaboration with the Gene Ontology Consortium
Protein Analysis THrough Evolutionary Relationships (PANTHER) is a comprehensive software system for inferring the functions of genes based on their evolutionary relationships.
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California’s Teaching Force 2010: Key Issues and Trends
This report covers four key themes: the contraction of the teacher workforce and other issues affecting the teacher supply pipeline, the weakening of the teacher development system in the context…
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Fiber Tracking Functionally Distinct Components of the Internal Capsule
To examine the microstructural condition of this fiber system and to test functional correlates of its sectors in health and aging, adults were examined with diffusion tensor imaging fiber tracking…
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Diagnostic-Photographic Determination of Drag/Lift/Torque Coefficients of a High Speed Rigid Body in a Water Column
A semi-empirical method is developed in this study to determine the drag/lift and torque coefficients for a fast-moving rigid body in a water column.
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A Comprehensive Rocket and Radar Study of Midlatitude Spread F
The new phase-sensitive ionosonde system operated at Wallops Island during the experiment confirms the long-standing hypothesis that this particular spread F event arises from multipath echoes distributed over a wide field of…
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H2B- and H3-Specific Histone Deacetylases Are Required for DNA Methylation in Neurospora Crassa
We created mutants of each of the four classical N. crassa HDAC genes and tested their effect on histone acetylation levels and DNA methylation.