Publications
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Ubiquitin Accumulation in Autophagy-Deficient Mice Is Dependent on the Nrf2-Mediated Stress Response Pathway: a Potential Role for Protein Aggregation in Autophagic Substrate Selection
We show that tissue-specific disruption of the essential autophagy genes Atg5 and Atg7 leads to the accumulation of all detectable Ub–Ub topologies, arguing against the hypothesis that any particular Ub linkage serves as a…
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EcoCyc: a Comprehensive Database of Escherichia Coli Biology
Recent improvements to the EcoCyc Web interface include combined gene/protein pages and a Regulation Summary Diagram displaying a graphical overview of all known regulatory inputs to gene expression and protein…
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The Rational Design of a Novel Potent Analogue of the 5′-AMP-Activated Protein Kinase Inhibitor Compound C with Improved Selectivity and Cellular Activity
We have designed and synthesized analogues of compound C, a non-specific inhibitor of 5′-AMP-activated protein kinase (AMPK), using a computational fragment-based drug design (FBDD) approach.
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Discovery of the FeO orange bands in the terrestrial night airglow spectrum obtained with OSIRIS on the Odin spacecraft
An unidentified pseudo-continuum in the 600 nm region is observed in the upper mesosphere with the limb-scanning OSIRIS imaging spectrograph on-board the Odin spacecraft.
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The Faraday Filter-Based Spectrometer for Observing Sodium Nightglow and Studying Atomic and Molecular Oxygen Associated with the Sodium Chemistry in the Mesopause Region
This paper describes the operational principles, design and field testing of a new, compact, Faraday filter-based spectrometer to measure the D2 (589.158 nm) to D1 (589.756 nm) intensity ratio of…
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From Handheld Collaborative Tool to Effective Classroom Module: Embedding CSCL in a Broader Design Framework
The field of Computer Supported Collaborative Learning (CSCL) includes designers who emphasize effectiveness, measured via experiments, as well as designers who emphasize context and conduct qualitative research on teaching and…
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Preonset Time Sequence of Auroral Substorms: Coordinated Observations By All-Sky Imagers, Satellites, and Radars
We show that longitudinally narrow flow bursts in the nightside polar cap can precede poleward boundary intensifications that are followed by equatorward moving north-south arcs.
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AI – space odyssey (guest editorial)
This special issue covers semantic technologies, including natural language processing, sophisticated on-board fault management, human-robotic interaction, and agent-based simulation architectures.
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Study of inkjet printing parameters to fabricate LCD color filter
The source of luminance non-uniformity of color filters fabricated by inkjet printing technique is described and the methods to minimize this non-uniformity are presented.
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Named Data Networking (NDN) project
In this report, we have proposed a new Internet architecture called Named Data Networking (NDN) based on this simple change.
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Optical polarization characteristics of ultraviolet (In)(Al)GaN multiple quantum well light emitting diodes
The polarization of the in-plane electroluminescence of (0001) orientated (In)(Al)GaN multiple quantum well light emitting diodes in the UV-A and UV-B spectral range has been investigated.
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Inkjet-patterned, organic complementary circuits and non-volatile memory arrays based on ferroelectric field-effect transistors
Organic complementary circuits are demonstrated for integration with mechanical sensors to enable the fabrication of a sensor tape to detect mechanical impacts correlated to traumatic brain injury.