Biomedical sciences publications
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The Neurobiology of Sleep and Wakefulness
Control of sleep and wakefulness involves multiple systems, each of which presents vulnerability to sleep/wake dysfunction that may predispose to physical and/or neuropsychiatric disorders.
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Does Pain Vary across the Menstrual Cycle? A Review
Animal studies support both pronociceptive and antinociceptive actions of oestradiol and progesterone suggesting that the net effect of these hormones on pain is complex and likely depends on the interaction…
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Clinicopathological Features and Prognostic Implications of Raf Kinase Inhibitor Protein Downregulation in Tongue Squamous Cell Carcinoma
In the present study, the expression of RKIP in 85 pairs of TSCC and corresponding adjacent non-cancerous tissues, 30 matched metastatic lesions from the cervical lymph nodes and 32 oral…
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Monocyte Chemotactic Protein-Induced Protein 1 and 4 Form a Complex but Act Independently in Regulation of Interleukin-6 mRNA Degradation
Here we report that MCPIP1 interacts with MCPIP4 to form a protein complex but they act independently in regulation of IL-6 mRNA degradation.
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Preclinical evaluations to identify optimal linezolid regimens for tuberculosis therapy
Clinically relevant linezolid regimens were simulated in the in vitro hollow-fiber infection model (HFIM) system to identify the linezolid therapies that minimize toxicity, maximize antibacterial activity, and prevent drug resistance.
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Validation of Sleep-Tracking Technology Compared with Polysomnography in Adolescents
Objective- To evaluate the accuracy in measuring nighttime sleep of a fitness tracker (Jawbone UP) compared to polysomnography (PSG).
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What We Know About Primary Dysmenorrhea Today: A Critical Review
This review reports on current knowledge, particularly with regards to the impact and consequences of recurrent menstrual pain on pain sensitivity, mood, quality of life and sleep in women with…
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Challenges of Metagenomics and Single-Cell Genomics Approaches for Exploring Cyanobacterial Diversity
We briefly review current sequencing technologies and their innovative uses in genomics and metagenomics.
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Refining Measurement of Substance Use Disorders among Women of Child-Bearing Age Using Hospital Records: The Development of the Explicit-Mention Substance Abuse Need for Treatment in Women (EMSANT-W) Algorithm
This article presents the development of the Explicit Mention Substance Abuse Need for Treatment in Women (EMSANT-W), a gender-tailored tool based upon existing International Classification of Diseases, 9th Edition, Clinical…
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SR-2P vaginal microbicide gel provides protection against herpes simplex virus 2 when administered as a combined prophylactic and postexposure therapeutic
Here, we show that a dose of SR-2P administered 24 h prior to infection provides some protection against the virus, but to a lesser degree than SR-2P administered either once…
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Total Exposure Study Analysis Consortium: A Cross-Sectional Study of Tobacco Exposures
The Total Exposure Study was designed to estimate levels of biomarkers of tobacco-specific and non-specific exposure and of potential harm in U.S. adult current cigarette smokers and tobacco product non-users.
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Pathophysiology of L-dopa-induced motor and non-motor complications in Parkinson’s disease
The present review attempts to provide an overview of our current understanding of dyskinesia and other L-dopa-induced dysfunctions, a field that dramatically evolved in the past twenty years.