Publications
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Discovery and Optimization of Benzotriazine Di-N-Oxides Targeting Replicating and Nonreplicating Mycobacterium Tuberculosis
These data along with measurements of the physiochemical properties and pharmacokinetic profile demonstrate that BTOs have the potential to be developed into a new class of antitubercular drugs.
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Lead Optimization of Antimalarial Propafenone Analogues
Careful examination of the bioavailability, pharmacokinetics, toxicology, and efficacy of this series of compounds using rodent models revealed orally bioavailable compounds that are nontoxic and suppress parasitemia in vivo.
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Comparative Analysis of the Substrate Preferences of Two Post-Proline Cleaving Endopeptidases, Prolyl Oligopeptidase and Fibroblast Activation Protein Alpha
Post-proline cleaving peptidases are promising therapeutic targets for neurodegenerative diseases, psychiatric conditions, metabolic disorders, and many cancers.
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Cortical nNOS Neurons Co-Express the NK1 Receptor and are Depolarized by Substance P in Multiple Mammalian Species
To evaluate the degree of co-expression of nNOS and NK1 in the cortex among mammals, we used double immunofluorescence for nNOS and NK1 and determined the anatomical distribution in mouse,…
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Flexible x-ray detector array fabricated with oxide thin film transistors
A flat panel flexible x-ray image sensor fabricated with oxide thin film transistors (TFT) is described.
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Proactive insider threat detection through graph learning and psychological context
This paper proposes an approach that combines Structural Anomaly Detection (SA) from social and information networks and Psychological Profiling (PP) of individuals.
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Hummingbird: privacy at the time of Twitter
In this paper, we assess the loss of privacy in today's Twitter-like OSNs and describe an architecture and a trial implementation of a privacy-preserving service called Hummingbird.
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A comparative study for IEEE Map Data Representation SIG
This talk reviews the existing geospatial data representations proposed by OGC (Open Geospatial Consortium).
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Through the Azerothian looking glass: mapping in-game preferences to real world demographics
Examining how in-game behavior preferences map onto real world demographics provides important empirically-derived insights into how to match game-based mechanisms to target demographic segments.
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Online gaming motivations scale: development and validation
In this paper, we describe the development and validation of an online gaming motivations scale based on a 3-factor model.
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Understanding experts’ and novices’ expertise judgment of Twitter users
This paper presents an empirical study to understand the differences between experts and novices in judging expertise of Twitter authors.
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Preschool Classroom Behavioral Context and School Readiness Outcomes for Low-Income Children: A Multilevel Examination of Child- and Classroom-Level Influences
Guided by an ecological theoretical model, the authors used a series of multilevel models to examine associations among children’s individual problem behavior, the classroom behavioral context, and school readiness outcomes…