Publications
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Fragment-based screening for inhibitors of PDE4A using enthalpy arrays and X-ray crystallography
Here we have used enthalpy arrays, which are arrays of nanocalorimeters, to perform an enzyme activity based fragment screen for competitive inhibitors of phosphodiesterase 4A (PDE4A).
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Highly sensitive tactile sensors integrated with organic transistors
A capacitive pressure sensor with a nano-needle dielectric was successfully fabricated by a facile breath figures method and demonstrated a record sensitivity among polymer tactile sensors.
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Tweeting with Hummingbird: privacy in large-scale micro-blogging OSNs
In this paper, we assess privacy in today's Twitter-like OSNs and describe an architecture and a trial implementation of a privacy-preserving service called Hummingbird a variant of Twitter that protects…
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Time encoded multicolor fluorescence detection in a microfluidic flow cytometer
We present an optical detection technique that delivers high signal-to-noise discrimination to enable a multi-parameter flow cytometer that combines high performance, robustness, compactness and low cost.
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Measuring learning progressions using bayesian modeling in complex assessments
This research examines issues regarding model estimation and robustness in the use of Bayesian Inference Networks (BINs) for measuring Learning Progressions (LPs).
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Fast and private computation of cardinality of set intersection and union
This paper explores a few PSI-CA variations and constructs several protocols that are more efficient than the state-of-the-art.
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Gender-Stratified Gene and Gene-Treatment Interactions in Smoking Cessation
We conducted gender-stratified analyses on a systems-based candidate gene study of regions involved in nicotinic response and the brain—reward pathway in two randomized clinical trials of smoking cessation treatments (placebo,…
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Replaying the Fracture Process of a Failed Space Shuttle Orbiter Thruster
The work shows how a failure event can be replayed through fracture surface topography analysis, FRASTA, and how information on load conditions, relative crack growth rates, and fracture mechanics parameters…
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The DRD4 Exon III VNTR, Bupropion, and Associations with Prospective Abstinence
We used univariate, multivariate, and longitudinal logistic regression to evaluate effects on point prevalence and continuous abstinence at end of treatment in European ancestry participants in a trial randomizing participants…
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Catalytic Detoxification of Nerve Agent and Pesticide Organophosphates by Butyrylcholinesterase Assisted with Non-Pyridinium Oximes
In the present paper we show a comprehensive study on hydrolytic detoxification of nerve agent and pesticide OPs catalysed by purified hBChE in combination with novel non-pyridinium oxime reactivators.
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Implementation of an Augmented Reality System for Training Dismounted Warfighters
We describe the technical methods and experimental results on building an Augmented Reality Training system for training dismounts doing maneuver operations.
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Mathematics Teaching Practices with Technology That Support Conceptual Understanding for Latino/a Students
We analyze how three seventh grade mathematics teachers from a majority Latino/a, linguistically diverse region of Texas taught the same lesson.