Publications
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In Silico Systems Biology Approaches for the Identification of Antimicrobial Targets
We have compiled software tools and databases that are typically used for target identification through in silico analyses. We have also identified enzyme- and broad-spectrum metabolite-based drug targets that have…
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Characterization of a Diffusible Signaling Factor from Xylella Fastidiosa
We describe here the isolation and characterization of an X. fastidiosa DSF (XfDSF) as 2(Z)-tetradecenoic acid. This compound was isolated both from recombinant Erwinia herbicola expressing X. fastidiosa rpfF and…
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A systematic comparison of the MetaCyc and KEGG pathway databases
We present a comparison of the compound, reaction, and pathway content of MetaCyc version 16.0 and a KEGG version downloaded on Feb-27-2012 to increase understanding of their relative sizes, their…
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Query Answering in Object Oriented Knowledge Bases in Logic Programming: Description and Challenge for ASP
We give a description of this KB and ASP programs for a suite of queries that have been of practical interest.
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Substorm Imaging at 450 Mhz with the Electronically Steerable Poker Flat ISR
Using pulse-by-pulse steering, a dense grid of beam positions, and a judicious use of multiple frequency channels, PFISR can provide three-dimensional reconstructions of density, temperature, and flow fields at a…
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Visual Search and the Aging Brain: Discerning the Effects of Age-Related Brain Volume Shrinkage on Alertness, Feature Binding, and Attentional Control
Poorer conjunction, but not feature, search performance was related to older age and volume shrinkage of nodes in the dorsolateral processing stream.
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Groups: Knowledge Spreadsheets for symbolic biocomputing
Groups allows Pathway Tools users to define a group of objects (e.g. groups of genes or metabolites) from a Pathway/Genome Database.
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A New Stratospheric and Tropospheric NO2 Retrieval Algorithm for Nadir-Viewing Satellite Instruments: Applications to OMI
We describe a new algorithm for the retrieval of nitrogen dioxide (NO2) vertical columns from nadir-viewing satellite instruments.
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Modulation of the Cannabinoid Receptors by Hemopressin Peptides
The exciting finding of endocannabinoid system modulation by the nonapeptide hemopressin and its N-terminal extensions has highlighted the complexity of cannabinoid biology and pharmacology and sparked interest for therapeutic purposes.
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Meteorites from Mars Via a Natural Two-Stage Gas Gun
We conclude that Martian rocks could be accelerated by the expansion of supercritical water that was shock compressed by the impact of an asteroid or comet, as was originally proposed…
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Object-Oriented Knowledge Bases in Logic Programming
We describe the axiomatic content of a biology knowledge base that poses both theoretical and empirical challenges for knowledge intensive reasoning.
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A Systematic Quantitative Proteomic Examination of Multidrug Resistance in Acinetobacter Baumannii
We have compared the proteome of the multidrug resistant strain BAA-1605, with the proteome of the drug-sensitive strain ATCC 17978, using iTRAQ labeling and online 2D LC/MS/MS for peptide/protein identification.