Publications
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Differential Effects of Nocicetin/Orphanin FQ (NOP) Receptor Agonists in Acute Versus Chronic Pain: Studies with Bifunctional NOP/μ Receptor Agonists in the Sciatic Nerve Ligation Chronic Pain Model in Mice
We identified a novel nociceptin/orphanin FQ (NOP)/μ-opioid receptor agonist, SR 16435, with high binding affinity and partial agonist activity at both receptors.
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Isotopic Reinforcement of Essential Polyunsaturated Fatty Acids Diminishes Nigrostriatal Degeneration in a Mouse Model of Parkinson’s Disease
We tested the hypothesis that isotopic reinforcement, by deuteration of the bisallylic sites most susceptible to oxidation in PUFA may provide at least partial protection against nigrostriatal injury.
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Flexible printed electronics: from materials characterization to device integration
In this talk, I will present the advantages and limitations of printed devices, and then discuss how to integrate the individual components by using complementary organic semiconductor circuits.
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Solution-processed memristive junctions used in a threshold indicator
Memristive metal/oxide/metal structures were patterned by inkjet printing, and these printed crossbar junctions were characterized to infer ionic and electronic transport parameters such as mobility and ion distribution.
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Model-based systems engineering for the design and development of complex aerospace systems
This paper presents a model-based system-engineering framework that was developed as part of the META program.
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Proceedings of the Fifth International Conference on Provable Security (ProvSec)
The ProvSec conference provides a platform for researchers, scholars and practitioners to exchange new ideas for solving these problems in the provable security area.
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Finding credible information sources in social networks based on content and social structure
We conducted an experiment designed to measure the extent to which different factors in online social networks affect both explicit and implicit judgments of credibility.
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Rapid mixing of sub-microliter drops by magnetic micro-stirring
We demonstrate rapid mixing of sub-microliter droplets (250nl) using miniaturized magnetic stir bars (400 m by 200 m by 15 m).
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Biodistribution, Toxicology, and Radiation Dosimetry of 5-HT1A-Receptor Agonist Positron Emission Tomography Ligand [11C]CUMI-101
The Medical Internal Radiation Dose estimates indicate the maximum permissible single-study dosage of CUMI-101 in humans is 52 mCi with testes and urinary bladder as the critical organ for males…
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Sharing Models and Research to Build Leadership in Program Improvement
SRI designed an online community architecture that permits faculty from small departments in different community colleges to share ideas about how to integrate PBL into their classrooms. This presentation presents…
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Enteric Microbiome Metabolites Correlate with Response to Simvastatin Treatment
We used a targeted GC-MS metabolomics platform to measure a panel of metabolites that may predict variation in statin LDL-C lowering efficacy.
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Targeting the Nicotinic Alpha7 Acetylcholine Receptor to Enhance Cognition in Disease
The current review focuses on the neurobiology of the α7nAChR, its role in cognition and the development status of some of the most promising molecules advancing for the treatment of…