Publications
-
Unravelling Glucan Recognition Systems by Glycome Microarrays Using the Designer Approach and Mass Spectrometry
We describe construction of a "glucome" microarray, the first sequence-defined glycome-scale microarray, using a "designer" approach from targeted ligand-bearing glucans in conjunction with a novel high-sensitivity mass spectrometric sequencing method.
-
Discovery of the First Small-Molecule Opioid Pan Antagonist with Nanomolar Affinity at Mu, Delta, Kappa, and Nociceptin Opioid Receptors
Since this is the first ligand containing the trans-(3R,4R)-dimethyl-4-(3-hydroxyphenyl)piperidine opioid antagonist pharmacophore to have affinity for the NOP receptor, we explored the structural determinants of its NOP binding affinity.
-
Balanced Designs for Deeper Learning in an Online Introductory CS Course for Middle School Students
This paper describes our efforts to use the design-based research methodology to design a 6-week middle school course on the OpenEdX platform for blended in-class learning.
-
Creating Writing Items of Graduated Complexity for Students with Significant Cognitive Disabilities
This paper presents: a design methodology for improving the validity of inferences about the performance of students with significant cognitive disabilities on large-scale ELA writing assessments...
-
ICN Hop by Hop Fragmentation
This document describes a hop-by-hop fragmentation scheme for ICN and mappings to the CCNx 1.0 and to the NDNTLV packet format.
-
Creating Value Together: The Emerging Design Space of Peer-to-Peer Currency and Exchange
We consider alternative and complementary currency and exchange innovations, including local/community currencies, timebanks, crypto-currencies, and person-to-person collaborative economy microenterprises, as a technology design space for currency and exchange
-
The SRI biofrustration corpus: Audio, video and physiological signals for continuous user modeling
We describe the SRI BioFrustration Corpus, an inprogress corpus of time-aligned audio, video, and autonomic nervous system signals recorded while users interact with a dialog system to make returns of…
-
Blueswitch: Enabling Provably Consistent Configuration of Network Switches
In this paper, we focus on the behavior of individual switches, and demonstrate that even simple rule updates result in inconsistent packet switching in multi-table datapaths.
-
Predicting the Academic Achievement of Deaf and Hard-of-Hearing Students from Individual, Household, Communication, and Educational Factors
Research suggests that the academic achievement of deaf and hard-of-hearing (DHH) students is the result of a complex interplay of many factors.
-
Beyond the PDP-11: Architectural Support for a Memory-Safe C Abstract Machine
We propose a new memory-safe interpretation of the C abstract machine that provides stronger protection to benefit security and debugging.
-
California College and University Collaborations: Facilitators, Challenges, and Impact on Student Mental Health
Reports on an evaluation of student mental health collaboration activities among California higher education systems, community agencies, and county mental health.
-
Pharmacokinetics and Metabolism of 4R-Cembranoid
The purpose of this study was to examine the metabolism and pharmacokinetics of 4R as part of its preclinical development as a neuroprotective drug.