Publications
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White Matter Microstructural Recovery with Abstinence and Decline with Relapse in Alcohol Dependence Interacts with Normal Ageing: A Controlled Longitudinal DTI Study
Background Alcohol dependence exacts a toll on brain white matter microstructure, which has the potential of repair with prolonged sobriety. Diffusion tensor imaging (DTI) enables in-vivo quantification of tissue constituents…
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PreK– 3 Family Engagement and Literacy
The McKnight Foundation’s Education and Learning (E&L) Program is promoting family engagement as part of a literacy initiative that spans from prekindergarten through third grade (PreK–3).
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Building a Breathprint: Biomarkers of Exposure Due to the Toxicant Trochloroethylene
Our pilot studies indicate that we can detect TCE and other VOCs in the breath environment that are indicative of neuronal degeneration. Pending studies will investigate the relationship between toxicant exposure…
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Development of an Agonist of the TGF-Beta Signaling Pathway to Treat Alzheimer’s Disease
Alzheimer’s disease (AD) is a neurodegenerative disorder that leads to progressive cognitive dysfunction. Current knowledge of the processes leading to AD is still limited, and no effective treatments are available.…
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PreK– 3 Teacher Instructional Practices
A key component of the McKnight Foundation’s Education and Learning (E&L) Program is supporting PreK–3 teachers to improve their literacy instruction in order to develop proficient readers.
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Research Brief: Implementation of the New Educator Evaluation System in Massachusetts
During the 2013-14 school year, the second year of the study, the research team conducted educator interviews and focus groups in 12 Massachusetts case study districts.
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A Top to Bottom Evaluation of IRI 2007 within the Polar Cap
This analysis demonstrates notable differences between IRI and ionosonde NmF2 diurnal and seasonal behavior over the entire period studied, where good agreement is found during summer periods but otherwise errors in…
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5′-AMP-Activated Protein Kinase (AMPK) Supports the Growth of Aggressive Experimental Human Breast Cancer Tumors
Here, we used triple-negative human breast cancer cells in which AMPK activity had been knocked down to investigate the contribution of AMPK to experimental tumor growth and core glucose metabolism.
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Digital Fabrication of Flexible Electronic Systems
In this talk, the speaker will discuss PARC's approach to circuit design and modeling in the context of building sensor systems in partnership with Thinfilm Electronics based on an ink-jet…
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Model-Based Approach for Optimal Maintenance Strategy
In this paper we introduce a novel model-based reliability analysis methodology to guide the best maintenance practices for the different components in complex engineered systems.
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Evaluation of Functional Activity and Aggregation Properties of Hemopressin
We tested the hemopressin peptide for CB1 receptor agonist and antagonist activity in cAMP and β-arrestin recruitment assay and found it to be inactive.
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Identifying User Demographic Traits through Virtual-World Language Use
The paper presents approaches for identifying real-world demographic attributes based on language use in the virtual world.