Publications
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A Bayesian method for identifying missing enzymes in predicted metabolic pathway databases
We have developed a method that efficiently combines homology and pathway-based evidence to identify candidates for filling pathway holes in Pathway/Genome databases.
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Towards a Quantitative Platform Independent Analysis of Knowledge Systems
The Halo Pilot collaboratively developed a taxonomy of failures with the goal of creating a common framework of metrics against which we could measure inter- and intra- system failure characteristics…
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Toward a Theory of Qualitative Reasoning about Plans
We define a qualitative framework for reasoning about plan structure, defining a set of plan relations that characterize key interactions among plan components and a calculus for reasoning qualitatively about…
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A Multimodal Learning Interface for Sketch, Speak and Point Creation of a Schedule Chart
We present a video demonstration of an agent-based test bed application for ongoing research into multi-user, multimodal, computer-assisted meetings.
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Computational Prediction of Human Metabolic Pathways from the Complete Human Genome
We present a computational pathway analysis of the human genome that assigns enzymes encoded therein to predicted metabolic pathways.
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Exploring Assignments, Student Work, And Teacher Feedback In Reforming Schools: 2002-03 Data From Washington State
We are working with foundation officials and reformers across the country to study high school change and what it takes to improve teaching and learning. We are examining the extent…
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Project Halo: Towards a Digital Aristotle
Project Halo is a multi-staged effort, sponsored by Vulcan Inc, aimed at creating the Digital Aristotle, an application that will encompass much of the world's scientific knowledge and be capable…
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Teacher Assignments And Student Work As Measures Of Opportunity To Learn
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Technology’s Contribution To Teaching And Policy: Efficiency, Standardization, Or Transformation?
We begin this chapter with a brief sketch of alternative perspectives on the ways in which technology can support education policy and practice. We will suggest that the connection between…
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Trained Named Entity Recognition Using Distributional Clusters
This work applies boosted wrapper induction (BWI), a machine learning algorithm for information extraction from semi-structured documents, to the problem of named entity recognition.
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Call for an enzyme genomics initiative
I propose an Enzyme Genomics Initiative, the goal of which is to obtain at least one protein sequence for each enzyme that has previously been characterized biochemically.
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Deductive Question Answering from Multiple Resources
Questions in natural language are answered by consulting multiple sources and inferring answers from information they provide. An automated deduction system, equipped with an axiomatic application-domain theory, serves as the…