Publications
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Novel Alpha 3 Beta 4 Nicotinic Acetylcholine Receptor-Selective Ligands. Discovery, Structure-Activity Studies, and Pharmacological Evaluation
We report the discovery and SAR of a novel class of compounds that bind to the α3β4 nAChR and have no measurable affinity for the α4β2 or α7 subtype.
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The ATE Suitability Inventory: A Tool for Analyzing Features of Workforce Education Instructional Materials
SRI International developed and tested a system for summarizing the key components of technician education instructional materials by providing a valid checklist.
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A Systematic Study of Genome Context Methods: Calibration, Normalization and Combination
We present a thorough study of the four main families of genome context methods found in the literature: phylogenetic profile, gene fusion, gene cluster, and gene neighbor.
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Signs of Preclinical Wernicke’s Encephalopathy and Thiamine Levels as Predictors of Neuropsychological Deficits in Alcoholism Without Korsakoff’s Syndrome
The purpose of this study was to determine whether meeting historical criteria for unsuspected Wernicke's encephalopathy explains why some alcoholics have severe neuropsychological deficits.
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Fine-Grained Tracking of Grid Infections
We describe three optimizations that together allow fine-grained tracking of the sources of anomalous activity in a Grid, thereby facilitating precise responses.
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Using large-scale databases in evaluation: Advances, opportunities, and challenges
The authors illustrate through examples both the opportunities provided by higher quality, interoperable data systems and the challenges encountered when using databases to identify issues of concern, test the plausibility…
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Multi-Modal Sensor Fusion Algorithm for Ubiquitous Infrastructure-Free Localization in Vision-Impaired Environments
In this paper, we present a unified approach for a camera tracking system based on an error-state Kalman filter algorithm.
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Efficient Sparse Pose Adjustment for 2D Mapping
In this paper, we propose an efficient method for constructing and solving the linear subproblem, which is the bottleneck of these direct methods.
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A Parallel Chiral-Achiral Liquid Chromatographic Method for the Determination of the Stereoisomers of Ketamine and Ketamine Metabolites in the Plasma and Urine of Patients with Complex Regional Pain Syndrome
A parallel chiral/achiral LC–MS/MS assay has been developed and validated to measure the plasma and urine concentrations of the enantiomers of ketamine, (R)- and (S)-Ket, in complex regional pain syndrome…
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Radar Detection of a Localized 1.4 Hz Pulsation in Auroral Plasma, Simultaneous with Pulsating Optical Emissions, During a Substorm
A ground based diagnostic of kilometer-scale oscillating electric fields would be a valuable tool in the study of pulsations and the auroral substorm.
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Rock-Solid Support: Florida District Weighs Effectiveness Of Science Professional Learning
Professional development that is both content-specific and anchored in what teachers must do in the classroom is becoming the norm for helping teachers improve their science instruction.
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Supporting Generative Thinking About the Integer Number Line in Elementary Mathematics
This report provides evidence of the influence of a tutorial “communication game” on fifth graders’ generative understanding of the integer number line. Analyses of micro-constructions during play revealed properties of…