Publications
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Performance of Fitbit Charge 3 Against Polysomnography in Measuring Sleep in Adolescent Boys and Girls
We evaluated the performance of Fitbit Charge 3™ (FC3), a multi-sensor commercial sleep-tracker, for measuring sleep in adolescents against gold-standard laboratory polysomnography (PSG).
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NK-Cell Biofactory as an Off-the-Shelf Cell-based Vector for Targeted In Situ Synthesis of Engineered Proteins
NK-cell Biofactory is an off-the-shelf allogeneic platform for cell-based synthesis of desired protein following recognition of a target cell while conserving the cytolytic activity.
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Innovations in Early Mathematics: Final Report
SRI evaluated the impact of teachers’ participation in a 2-year professional development (PD) intervention to improve teachers’ knowledge, attitudes, and instructional practice in math across prekindergarten (preK) to third grade…
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Modular Adaptation for Cross-Domain Few-Shot Learning
While literature has demonstrated great successes via representation learning, in this work, we show that improvement of downstream tasks can also be achieved by appropriate designs of the adaptation process.
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Designing Schools with and for Students: Lessons Learned from the Engage New England Initiative
This research brief identifies promising strategies for embracing student voice in school design based on the experience of Engage New England (ENE) grantees.
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The BioCyc Metabolic Network Explorer
The Metabolic Network Explorer is a new addition to the BioCyc.org website and the Pathway Tools software suite that supports the interactive exploration of metabolic networks.
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Confidence Calibration for Domain Generalization under Covariate Shift
We present novel calibration solutions via domain generalization. Our core idea is to leverage multiple calibration domains to reduce the effective distribution disparity between the target and calibration domains for…
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Neurofunctional characteristics of executive control in older people with HIV infection: a comparison with Parkinson’s disease
Expression of executive dysfunctions is marked by substantial heterogeneity in people living with HIV infection (PLWH) and attributed to neuropathological degradation of frontostriatal circuitry with age and disease.
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Portable Magnetometry for Detection of Biomagnetism in Ambient Environments
This paper presents a method of optical magnetometry that is able to detect biomagnetic signals generated from the human brain and heart in Earth’s ambient environment.
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Pathway Size Matters: The Influence of Pathway Granularity on Over-Representation (Enrichment) Statistics
We show that alternative pathway definitions can alter enrichment p -values by up to nine orders of magnitude, whereas statistical corrections typically alter enrichment p -values by only two orders…
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Leveraging Curation Among Escherichia coli Pathway/Genome Databases Using Ortholog-Based Annotation Propagation
We have developed a method to automatically propagate multiple types of curated knowledge from genes and proteins in one genome database to their orthologs in uncurated databases for related strains,…
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Prediction of Selected Biosynthetic Pathways for the Lipopolysaccharide Components in Porphyromonas gingivalis
We use bioinformatics tools to predict biosynthetic pathways for the production of the normal (O-type) lipopolysaccharide in the W50 strain Porphyromonas gingivalis and compare the pathway with other putative pathways…